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Evolution

Lassa virus ecology study out in Nature Comms Lassa ecology mapPress ReleasesPublications

Lassa virus ecology study out in Nature Comms

New analysis by scientists at Scripps Research and University of Brussels finds that climate change and other factors could soon make deadly Lassa fever a much bigger public health problem in Africa. In the study, which appeared on September 27, 2022, in Nature Communications, scientists analyzed decades of environmental data associated with Lassa virus outbreaks, revealing temperature, rainfall and the presence…
October 3, 2022
SARS-CoV-2 ‘origin’ studies out in Science SARS-CoV-2Press ReleasesPublications

SARS-CoV-2 ‘origin’ studies out in Science

The COVID-19-causing coronavirus, SARS-CoV-2, likely first spread to humans from animals in two separate transmission events in a Wuhan market in late November 2019, according to a pair of analyses by international teams co-led by Scripps Research scientists. The analyses, published July 26, 2022 in Science and released in earlier, pre-print versions in February, were based mainly on the locations of cases…
July 29, 2022
SARS-CoV-2 early epidemic study out in Cell Catie AndersonPublications

SARS-CoV-2 early epidemic study out in Cell

Our study investigating one of the most explosive early COVID-19 outbreaks in the United States has been published in Cell. The emergence of the COVID-19 epidemic in the U.S. went largely undetected due to inadequate testing. New Orleans experienced one of the earliest and fastest accelerating outbreaks, coinciding with Mardi Gras. To gain insight into the emergence of SARS-CoV-2 in…
July 30, 2021
Zika papers in Nature 2017-Nature-celebrationPublications

Zika papers in Nature

In a series of papers in the journals Nature and Nature Protocols, we used Zika virus sequencing from patients and mosquitos to show how the virus has spread across South America and into Florida. This work was performed as a large (huge!) collaboration of national and international institutions, which was made possible because of open science and open data. (more…)
May 25, 2017
Ebola paper in Cell Cell abstractPublications

Ebola paper in Cell

In a recent study published in Cell together with colleagues from UMass Worcester and the Broad, we show how a single mutation that occurred during the 2013-2016 Ebola virus disease epidemic in West Africa increased the ability of the virus to infect human cells. The mutation occurred in the Ebola virus glycoprotein and is located in the receptor binding domain of…
November 22, 2016
Review on Ebola evolution in Nature Nature paperPublications

Review on Ebola evolution in Nature

The 2013-2016 Ebola epidemic in West Africa was of unprecedented size and devastation, but also stands a landmark for infectious disease genomics. By sequencing virus genomes directly from patient samples, scientists are now able to investigate how viruses evolve, transmit between individuals, and spread across country borders during outbreaks, directly informing infection control. (more…)
October 12, 2016
Ebola paper out in Cell Publications

Ebola paper out in Cell

In a large collaboration between the Viral Hemorrhagic Fever Consortium, Kenema Government Hospital, Harvard University, Broad Institute, Tulane University, Edinburgh University, the CDC, USAMRIID, and others we have just published a paper in Cell detailing the epidemiology, transmission, and evolution of Ebola virus over seven months in Sierra Leone.  (more…)
June 18, 2015
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