Andersen Lab

We are using infectious disease genomics to investigate how pathogenic viruses such as Zika, West Nile, Ebola, Lassa, and HCoV-19/SARS-CoV-2 emerge and cause large-scale outbreaks. Using a combination of computational biology, experimentation, and field work, our hope is to transform outbreak response and change the way we develop vaccines and therapeutics.

Andersen Lab at Scripps Research

Welcome to the Andersen Laboratory

At the Andersen Lab at Scripps Research we try to understand questions such as: how do viruses emerge, spread, evolve, and go from causing small-scale outbreaks to large-scale epidemics? How can we diagnose them better and discover novel ones? How do they develop resistance to countermeasures and what molecular and immunological factors govern the underlying mechanisms? Critically, by addressing these questions, can we develop new and effective vaccines and medicines, while informing outbreak responses? The research in our laboratory is aimed at tackling these questions using an integrated approach of computation, experimentation, genomics, and large-scale data analysis. We also more broadly employ quantitative approached across scientific disciplines, ranging from microbiology to human immunology and genetics.

The Andersen Laboratory was established at Scripps Research in the summer of 2015 in beautiful La Jolla, California. We are strong proponents of open data and open science, and we are big believers in collaborating across scientific disciplines. To this end, we are actively engaged in several of our research initiatives, including the Center for Viral Systems Biology, the Viral Hemorrhagic Fever Consortium, and the WestNile 4K Project.

Ready to learn more about the lab? Check out the people working here, our research, publications, and data.

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Torrey-Pines
Training

CViSB Systems Biology Workshop

We are pleased to announce the 2nd annual CViSB Systems Biology workshop February 24-26, 2020 in La Jolla, CA. This two-and-a-half day workshop will emphasize computational systems biology approaches to improved understanding of host response to viral infection, across a spectrum of methods and applications.  (more…)
Cell abstract
Publications

Zika surveillance study in Cell

Our study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika epidemic in…
CViSB workshop
News

CViSB year in review

The first year of CViSB has been a busy one. Receiving the NIH grant in February, 2018 prompted the onboarding of new scientists, research trips to West Africa, and a myriad of planning and coordination meetings. Samples from over 250 Lassa and Ebola patients were collected during trips to Kenema Government Hospital (KGH). The samples will be used to generate…