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We are using pathogen genomics to investigate how viruses such as Zika, West Nile, Ebola, Lassa, SARS-CoV-2, and monkeypox emerge and cause large-scale outbreaks. Using a combination of computational biology, experimentation, and field work, we aim to transform outbreak response and change the way we develop countermeasures.

Andersen Lab at Scripps Research

Welcome to the Andersen Laboratory

At the Andersen Lab at Scripps Research we try to understand questions such as: how do viruses emerge, spread, evolve, and go from causing small-scale outbreaks to large-scale epidemics? How can we diagnose them better and discover novel ones? How do they develop resistance to countermeasures and what molecular and immunological factors govern the underlying mechanisms? Critically, by addressing these questions, can we develop new and effective vaccines and medicines, while informing outbreak responses? The research in our laboratory is aimed at tackling these questions using an integrated approach of computation, experimentation, genomics, and large-scale data analysis. We also more broadly employ quantitative approaches across scientific disciplines, ranging from microbiology to human immunology and genetics.

The Andersen Laboratory was established at Scripps Research in the summer of 2015 in beautiful La Jolla, California. We are strong proponents of open data and open science, and we are big believers in collaborating across scientific disciplines. To this end, we are actively engaged in several of our research initiatives, including the Global Health Initiative at Scripps Research, the Center for Viral Systems Biology, the Viral Hemorrhagic Fever Consortium, the West African Research Network for Infectious Diseases, and the WestNile 4K Project.

Ready to learn more about the lab? Check out the people working here, our research, publications, and data.

COVID-19 / SARS-CoV-2 Resources

To gain insights into the emergence, spread, transmission, and evolution of the COVID-19 pandemic, we are working with a large number of public health agencies, hospitals, biotechs, and academic partners. With funding from the CDC and NIH, we are sequencing hundreds of samples a week and all the data are made publicly available.

In response to the emergence of new variants of SARS-CoV-2, we have made several visualization tools to make the genomic data more useful to the public, scientists, and outbreak responders.

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News

Jyothi Purushotham and Holly Lutz recognized for career accomplishments

Congratulations to Jyothi Purushotham and Holly Lutz, two Andersen Lab postdoctoral researchers who recently received awards recognizing significant achievements in their respective areas of study. Jyothi Purushotham, PhD, was awarded the International Biomedical Research Alliance’s Outstanding Recent Graduate Award, an honor that aims to recognize those who embody scientific innovation and collaboration through significant early career discoveries. As an NIH-Oxford…
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Press Releases

Scripps Research receives $2.5M CDC contract for SARS-CoV-2 surveillance program

A team led by the Andersen Lab has been awarded a contract by the U.S. Centers for Disease Control & Prevention (CDC) in support of one of the largest SARS-CoV-2 surveillance programs in the United States. The two-year, $2.5 million contract will fund the large-scale, near real-time sequencing of SARS-CoV-2 isolates from hospitals and local public health agencies in San…
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Training

WARN-ID Genomic Epidemiology Training Lays Groundwork for Future Research

WARN-ID recently concluded a six-week genomic epidemiology training of  44 trainees across seven countries. The training was composed of three modules aimed at meeting the immediate need for SARS-CoV-2 sequencing, while also providing a vital foundation in genomics and bioinformatics for future development.  26 pre-recorded lecture videos, didactic sessions, office hours, supplemental materials, and ongoing support through a dedicated Slack…