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We are using pathogen genomics to investigate how viruses, including arenaviruses, filoviruses, coronaviruses, influenza viruses, orthopoxviruses, and arboviruses emerge, evolve, and cause large-scale outbreaks. Using a combination of computational biology, experimentation, and 'field' work, we aim to transform outbreak response and change the way we develop and apply effective countermeasures.

Andersen Lab at Scripps Research

At the Andersen Lab at Scripps Research we try to understand questions such as: how do viruses emerge, spread, evolve, and go from causing small-scale outbreaks to large-scale epidemics? How can we diagnose them better and discover novel ones? How do they develop resistance to countermeasures and what molecular and immunological factors govern the underlying mechanisms? Critically, by addressing these questions, can we develop new and effective vaccines and medicines, while informing outbreak responses? The research in our laboratory is aimed at tackling these questions using an integrated approach of computation, experimentation, genomics, and large-scale data analysis. We also more broadly employ quantitative approaches across scientific disciplines, ranging from microbiology to human immunology and genetics.

The Andersen Laboratory was established at Scripps Research in the summer of 2015 in beautiful La Jolla, California. We are strong proponents of open data and open science, and we are big believers in collaborating across scientific disciplines. To this end, we are actively engaged in several of our research initiatives, including the Global Health Initiative at Scripps Research, the Center for Viral Systems Biology, the Viral Hemorrhagic Fever Consortium, the West African Research Network for Infectious Diseases, SEARCH, and the WestNile 4K Project.

Ready to learn more about the lab? Check out the people working here, our research, publications, and data.

COVID-19 / SARS-CoV-2 Resources

People

Kristian

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Andrew

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Refugio

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Our Initiatives

News

2024 Interns
News

Welcome 2024 Summer Interns

Please join the Andersen Lab in welcoming the seven summer interns selected from the Scripps Research Translational Institute Student Research Internship Program! Chosen from a large pool of candidates from around the country, these keen aspiring scientists are motivated to learn from leading researchers at Scripps Research. The new interns are working closely with a mentor on either a wet…
Translational Institute
News

Translational science pilot study awards fuel innovation

Two early-stage scientists in the lab have been awarded grants for translational science research projects through the Scripps Research Translational Institute’s Pilot Study Award Program. The program supports scientists who strive to conduct transformative research with the potential to accelerate medical breakthroughs. Translational science is the process of turning observations in the laboratory into interventions, including new medicines, diagnostics or…
H5N1 tree
Narrative

Preliminary Report on H5N1 in Cattle

During the winter of 2020-2021, a new genotype of highly-pathogenic (HP) H5N1 avian influenza A virus emerged in Europe, comprising a reassortant between the epizootic HP clade 2.3.4.4b H5N8 and local low pathogenicity wildfowl strains. This new genotype caused record levels of infections in farmed poultry throughout Europe and quickly traveled, via waterfowl flyways, into North America, Africa and East…