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Ebola Archives | Andersen Lab

Ebola antibody research

By | Publications

In two papers published in Cell and Cell Host Microbe together with our collaborators at VIC, CViSB, and VHFC we describe in detail antibody responses to Ebola virus. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, we investigated which immunological features play key roles in protection against the virus. This was our first…

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CViSB established

By | Press Releases

Scripps Research scientists receive $15 million to study viral outbreak survivors. With a new $15 million grant, scientists at Scripps Research are gearing up for an in-depth study of survivors of viral outbreaks. The grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases will support the efforts of the Scripps Research-led Center for Viral Systems…

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Ebola paper in Cell

By | Publications

In a recent study published in Cell together with colleagues from UMass Worcester and the Broad, we show how a single mutation that occurred during the 2013-2016 Ebola virus disease epidemic in West Africa increased the ability of the virus to infect human cells. The mutation occurred in the Ebola virus glycoprotein and is located in the receptor binding domain of…

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Review on Ebola evolution in Nature

By | Publications

The 2013-2016 Ebola epidemic in West Africa was of unprecedented size and devastation, but also stands a landmark for infectious disease genomics. By sequencing virus genomes directly from patient samples, scientists are now able to investigate how viruses evolve, transmit between individuals, and spread across country borders during outbreaks, directly informing infection control.

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rates

Flawed Ebola study in Science

By | Publications

In a technical comment in Science, we show how a study published in 2015 by Hoenen, Feldmann, and others was based on faulty analyzes and a misunderstanding of the findings. The original article by the authors, as well as a later published erratum, failed to account for significant data analysis errors performed by Hoenen and colleagues. 

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Roots, Not Parachutes

By | Publications

Infectious disease outbreaks continue to pose challenges to global health and security, prompting reactive countermeasures. Recently, severe outbreaks of Ebola and Zika virus were designated by the World Health Organization as “Public Health Emergencies of International Concern.” Other emerging viral pathogens have warranted similar attention, including virus outbreaks from Lassa, Chikungunya, avian influenza, Nipah, SARS, and MERS.

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Feature in Politiken

By | News

The leading Danish newspaper Politiken had a feature on our work in the September 20th 2015 Sunday section. The article discusses our past and ongoing work with Lassa and Ebola. The full feature describes how we have investigated both Lassa and Ebola virus evolution based on our most recent papers in Cell and Science.

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Lassa paper on the front page of Cell

By | Publications

In a large multi-disciplinary collaboration between partners in Sierra Leone, Nigeria, USA, and Europe, we have published our first study on Lassa virus evolution. The paper – which appears on the front page of the August issue of Cell – is the result of seven years of work on Lassa fever across West Africa.

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