All Posts By

Kristian Andersen

Torrey-PinesTraining

CViSB Systems Biology Workshop

We are pleased to announce the 2nd annual CViSB Systems Biology workshop February 24-26, 2020 in La Jolla, CA. This two-and-a-half day workshop will emphasize computational systems biology approaches to improved understanding of host response to viral infection, across a spectrum of methods and applications.  (more…)
December 18, 2019
Cell abstractPublications

Zika surveillance study in Cell

Our study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika epidemic in…
August 23, 2019
CViSB workshopNews

CViSB year in review

The first year of CViSB has been a busy one. Receiving the NIH grant in February, 2018 prompted the onboarding of new scientists, research trips to West Africa, and a myriad of planning and coordination meetings. Samples from over 250 Lassa and Ebola patients were collected during trips to Kenema Government Hospital (KGH). The samples will be used to generate…
May 21, 2019
cvisb workshopNews

CViSB workshop

Together with Marc Suchard from UCLA, we’re pleased to host the upcoming CViSB “Systems Biology of Infectious Disease” workshop February 20-22, 2019 in La Jolla, CA. Those wanting to learn more about genomics and phylogenetic methods to analyze infectious diseases will not want to miss it! (more…)
December 10, 2018
Cell abstractPublications

Ebola antibody research

In two papers published in Cell and Cell Host Microbe together with our collaborators at VIC, CViSB, and VHFC we describe in detail antibody responses to Ebola virus. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, we investigated which immunological features play key roles in protection against the virus. This was our first…
August 10, 2018
figure 3Data

Hidden Zika outbreak

Summary: Using local and travel-associated case reporting from American and European public health systems, we identified an unreported Zika outbreak in Cuba during 2017. Virus sequencing from travelers revealed that the Zika outbreak in Cuba was sparked by multiple introductions of the virus from elsewhere in the Caribbean and Central America during 2016 that persisted into 2017. The recent Zika virus…
July 3, 2018
holmes nature commentaryPublications

Pandemics: Focus on surveillance

Over the past 15 years, outbreaks caused by viruses such as Ebola, SARS, and Zika have cost governments billions of US dollars. Combined with a perception among scientists, health workers and citizens that responses to outbreaks have been inadequate, this has fueled what seems like a compelling idea. Namely, that if researchers can identify the next pandemic virus before the…
June 11, 2018
Cell abstractPublications

Malaria paper in Cell

Hereditary xerocytosis is thought to be a rare genetic condition characterized by red blood cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced Plasmodium infection in vitro; however, the role of RBC dehydration in protection against malaria in vivo is unknown. Most cases of hereditary xerocytosis are associated with gain-of-function mutations in PIEZO1, a mechanically activated ion channel. We…
April 12, 2018