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SARS-CoV-2Press ReleasesPublications

SARS-CoV-2 studies from the Middle East out in Nature Comms

Understanding the global transmission of SARS-CoV-2 is critical for rapidly containing and handling the virus, especially as new variants and mutations of concern emerge. Certain regions in the world, including the Middle East and Northern Africa region, have been notoriously understudied and under-sampled. For the first time, Scripps Research scientists and collaborators unveil how the virus spreads in this region…
September 3, 2022
SARS-CoV-2Press ReleasesPublications

SARS-CoV-2 ‘origin’ studies out in Science

The COVID-19-causing coronavirus, SARS-CoV-2, likely first spread to humans from animals in two separate transmission events in a Wuhan market in late November 2019, according to a pair of analyses by international teams co-led by Scripps Research scientists. The analyses, published July 26, 2022 in Science and released in earlier, pre-print versions in February, were based mainly on the locations of cases…
July 29, 2022
SARS2 surveillancePress ReleasesPublications

SARS-CoV-2 surveillance study out in Nature

It can be a bit smellier than other ways of monitoring COVID-19, but analyzing wastewater is a cheaper, faster and more accurate way for public health officials and researchers to detect rising cases. Bits and pieces of the SARS-CoV-2 virus are flushed down toilets and washed down sinks by infected individuals; more copies of the virus found in sewage means…
July 13, 2022
Catie AndersonPublications

SARS-CoV-2 early epidemic study out in Cell

Our study investigating one of the most explosive early COVID-19 outbreaks in the United States has been published in Cell. The emergence of the COVID-19 epidemic in the U.S. went largely undetected due to inadequate testing. New Orleans experienced one of the earliest and fastest accelerating outbreaks, coinciding with Mardi Gras. To gain insight into the emergence of SARS-CoV-2 in…
July 30, 2021
Cell abstractPublications

Zika surveillance study in Cell

Our study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika epidemic in…
August 23, 2019
Cell abstractPublications

Ebola antibody research

In two papers published in Cell and Cell Host Microbe together with our collaborators at VIC, CViSB, and VHFC we describe in detail antibody responses to Ebola virus. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, we investigated which immunological features play key roles in protection against the virus. This was our first…
August 10, 2018
Cell abstractPublications

Malaria paper in Cell

Hereditary xerocytosis is thought to be a rare genetic condition characterized by red blood cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced Plasmodium infection in vitro; however, the role of RBC dehydration in protection against malaria in vivo is unknown. Most cases of hereditary xerocytosis are associated with gain-of-function mutations in PIEZO1, a mechanically activated ion channel. We…
April 12, 2018
Cell abstractPublications

Zika genomics commentary in Cell

The emergence and spread of Zika virus in the Americas continues to challenge our disease surveillance systems. Virus genome sequencing during the epidemic uncovered the timescale of Zika virus transmission and spread. Yet, we are only beginning to explore how genomics can enhance our responses to emerging viruses. Together with our colleagues Nuno Faria and Oliver Pybus at the University…
March 12, 2018